Workshop 7:Living Cell-based Microrobotics for Precise Medical Therapeutics
Organizers: Jong-Oh Park
Timeslot: 14:30 – 17:30
Room: Carré 2L
Biomedical microrobotics has attracted great interest because of the invasiveness and high targeting efficiency. However, the development of microrobots still has problems, such as difficulty in fabrication of high controllability, reliability, and efficiency containing microactuators and microsensors using biodegradable and biocompatible materials, and in meeting the critical requirements related to several theragnostic properties. To overcome the challenges of scaling down robotic and other functional devices, living cells-based microrobots have received significant attentions because of their strong merits: biocompatible, biodegradable, self-sensing, self-actuation, and theragnostic properties. In this workshop, three different specific cells for microrobot will be discussed; Bacterial cell, immune cell, and stem cell. The bacterial cells and immune cells have great potential abilities such as natural sensing the tumor, migrating deep into the tumor, and exerting cytotoxic effects on tumor. Therefore, first two topics will be focused on how to utilize these abilities of the bacterial and immune cells with robot-technology, respectively, in order to realize the localization of therapeutic agents to the tumor lesion and prevention of the spread of therapeutic agents into normal tissues in short time period with high targeting capability. Moreover, autologous cell-based therapy, which uses stem cell, has attracted great interest in tissue regeneration. One of the challenging issues for the stem cell therapy, however, is to deliver the large amounts of the cell to the defect region with minimally invasive way. Hence, the last topic will be discussed with how to actively and precisely deliver the stem cell to the target region by the operator’s control.